It depends on your overall state of health, the size and spread of the mesothelioma recurrence, and what type of treatment you have already had. It also depends on what you want to do. You might be given different chemotherapy. If there is a visible tumor, it might be removed surgically.
There are clinical trials that include people whose mesothelioma has recurred after initial treatment. Your doctors may suggest a clinical trial. At the same time, you may want to look for one yourself.